Transcription profiling of mouse interferon-I?-dependent regulatory circuits in immune inflammation highlighted in diabetes

ChEBI2008-11-13 更新2026-07-21 收录

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Transcription profiling of mouse interferon-I?-dependent regulatory circuits in immune inflammation highlighted in diabetes

创建时间：

2008-11-13

Additional file 7 of Dynamic rewiring of the human interactome by interferon signaling

Additional file 7. Gene Ontology terms differentially enriched between unstimulated and IFN-stimulated interactomes.

DataCite Commons2020-08-25 更新110

Transcriptional profile of MORC3 deficient BLaER1 monocytes [KO]. Transcriptional profile of MORC3 deficient BLaER1 monocytes [KO]

We have identified MORC3 as a negative regulator of Type I Interferon (IFN), whose absence induces IFN and interferon-stimulated genes (ISGs). To study the global transcriptional effects of loss of MO

NIAID Data Ecosystem100

Type I interferon (IFN) response in USP18 knockout in MDA-MB-231 breast cancer cells [RNA-seq]. Type I interferon (IFN) response in USP18 knockout in MDA-MB-231 breast cancer cells [RNA-seq]

Type I IFN induces IFN stimulated genes (ISGs) and exert varieties of immunomoduratory functions. However, it is not well characterized how ISGs are regulated by negative regulators of IFN signaling.

NIAID Data Ecosystem80

Additional file 8 of Dynamic rewiring of the human interactome by interferon signaling

Additional file 8. Immunoprecipitation-mass spectrometry of four core ISGs (IFI35, STAT1, NMI, and PNPT1) in IFN-stimulated and unstimulated cells.

DataCite Commons2020-08-25 更新100

Table_1_High Dose IFN-β Activates GAF to Enhance Expression of ISGF3 Target Genes in MLE12 Epithelial Cells.xlsx

Interferon β (IFN-β) signaling activates the transcription factor complex ISGF3 to induce gene expression programs critical for antiviral defense and host immune responses. It has also been observed t

NIAID Data Ecosystem90