Response of yeast to saponin treatment

Genome-wide expression profiling was used to identify genes that showed altered expression in response to treatment with the saponins tomatidine, tomatine and the sterol biosynthesis inhibitory compound fenpropimorph Growth inhibition by the compounds was monitored by measuring the OD600nm本研究采用全基因组表达谱分析（Genome-wide expression profiling），以鉴定经皂苷类化合物番茄啶（tomatidine）、番茄苷（tomatine）以及固醇生物合成抑制剂（sterol biosynthesis inhibitory compound）芬普莫芬（fenpropimorph）处理后，表达水平发生改变的基因；同时通过测定600纳米处的光密度（OD600nm），监测上述化合物的生长抑制情况。