PMACS-71
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<b>Project title</b>: PMACS-71<b>Grant Information:</b> AHA Grant 9TPA34910007, Regulatory role of pericardial macrophages in myocardial infarction<b>Project Description:</b>· Animal Model: Myocardial Infarction· Animal Age: 8-12 Weeks· Animal Sex: Male· Animal Strain: C57B6/J Lys<sup>Cre</sup>GATA6<sup>fl/fl</sup>· Number: 8 Mice· Groups: 5 Lys<sup>Cre</sup>GATA6<sup>fl/fl</sup> receiving CCL2-neutralizing antibody, 3 Lys<sup>Cre</sup>GATA6<sup>fl/fl </sup>mice receiving no CCL2, all infarcted· Experimental Conditions: Mice were given MI via LAD ligation. One group of mice also received 30uL of 0.02mg/kg CCL2-neutralizing antibody into the pericardial cavity during surgery. Animals were sacrificed at day 2 post-infarction. Hearts were collected and analyzed via Flow Cytometry.<b>Code/Scripts: </b>N/A<b>Licenses: </b>N/A<br><br>



