Tissue-specific changes in Tcrb conformation

NIAID Data Ecosystem2026-03-11 收录

T细胞发育

受体构象动态

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE68955 数据链接链接失效反馈

官方服务：

资源简介：

We report the changes in Tcrb interactome upon transitioning from DN to DP stage of thymocyte development Examination of the interactomes of Eb and Trbv5 viewpoints in RAG-deficient DN and DP thymocytes

创建时间：

2019-05-15

RNA-seq and anti-LMO2 ChIP-seq data in primary T cells in different stages from LMO2 over-expressing C57BL/6J transgenic mice. RNA-seq and anti-LMO2 ChIP-seq data in primary T cells in different stages from LMO2 over-expressing C57BL/6J transgenic mice

T细胞发育

转录组与ChIP测序分析

In this study, to investigate the pathogenic role of transcriptional regulator LMO2 during T lineage development, we isolated DN1, DN3, DP, CD4SP, CD8SP thymocytes, splenic CD4+ T cells and splenic CD

NIAID Data Ecosystem60

Expression data from WT and E2A-deficient murine DN2 cells. Mus musculus

T细胞发育

E2A转录因子调控

The E2A transcription factors promote the development of thymus-seeding cells but it remains unknown whether these proteins play a role in T lymphocyte lineage specification or commitment. By examinin

NIAID Data Ecosystem30

Human Early Postnatal Thymus [CITE-seq]

T细胞发育

胸腺微环境多组学

Within the thymus, regulation of the cellular cross-talk directing T cell development is dependent on spatial interactions within specialized niches. To create a holistic, spatially defined map of tis

NIAID Data Ecosystem20

Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of Treg development

自身免疫

T细胞发育

Thymic education of Tregs is superior to negative selection in the prevention of autoimmunity. To address this hypothesis, TCR repertoires of thymic and peripheral Tcells (including Tregs) from condit

NIAID Data Ecosystem40

Single-cell RNA-sequencing of mouse double-negative developing thymocytes

单细胞转录组学

T细胞发育

We performed a single-cell transcriptome analysis of double-negative developing thymocytes from the DN2, DN3 and DN4 populations Double-negative developing thymocytes from the DN2, DN3 and DN4 populat

Alliance of Genome Resources20

Tissue-specific changes in Tcrb conformation

资源简介：

相关数据集