We systematically benchmarked seven high-throughput single-cell RNA-seq methods. We prepared 21 libraries under identical conditions of a defined mixture of two human and two murine lymphocyte cell li
We report the RNA sequencing of ex vivo sorted B cells isolated from melanoma patients within the tumoral tissue or the blood. Sorted B cells from healthy donor blood were included as control. Transcr
Developmental transitions can be described in terms of morphology and individual genes expression patterns, but also in terms of global transcriptional and epigenetic changes. Most of the large-scale
T cell dysfunction is a hallmark of many cancers. Features of dysfunctional T cells and mechanisms leading to T cell dysfunction remain incompletely understood. Significant chromatin changes happen wh
