Background: Colorectal cancers are believed to arise predominantly from adenomas. Although these precancerous lesions have been subjected to extensive clinical, pathological, and molecular analyses, l
Background Oncogenes drive cancer progression, but few are active exclusively in tumor cells. Connexins (Cxs), traditionally recognized as ion channel proteins, can localize to the nucleus and regula
Vegetative hyphae of PH-1, Fgsrp2 and Fgsrp1srp2 mutants were harvested from 16-hour YEPD cultures. Total RNA samples were extracted with the Qiagen RNeasy Micro kit and poly(A)+ mRNA was enriched wit
We tamoxifen treated 8-12 week old mice that had floxed alleles of the following: 1) both Apc alleles (giving rise to Apc truncation/inactivation); 2) both Cdx2 alleles (giving rise to Cdx2 inactivati