Over-expression of CTR1 delta-300 alters element and transcription profiles in yeast

In an approach to generate Saccharomyces cerevisiae strains with increased intracellular copper amounts for technical applications we over-expressed the copper transporter CTR1 and a variant of CTR1 with a truncation in the C-terminus after the 300 amino acids (CTR1 delta-300)为构建可用于工程应用的胞内铜含量提升的酿酒酵母（Saccharomyces cerevisiae）菌株，本研究过表达了铜转运蛋白CTR1，以及在第300位氨基酸后进行C端截短的CTR1变体（CTR1 delta-300）。