Gene Ontology enrichment analyses of genes showing the greatest increase and decrease in expression following adaptation.

Genes +/−1.5 SD from the mean of summed expression changes across all experiments were analyzed for statistically significant GO term enrichment by computing a p-value using the hypergeometric distribution (The background set of genes was 5443, the number measured in microarray experiments). Nonredundant, statistically significant enriched GO terms (Bonferonni corrected p<0.01) are listed below. The number of genes annotated to each GO term that were +/−1.5 SD from the mean (Nclass) were divided by the number of genes within the genome that are annotated to that GO term (Ngenome) to determine a fractional representation of each term (%).