Zhang2007 - Mechanism of DNA damage response (Model1)

NIAID Data Ecosystem2026-05-02 收录

DNA损伤响应

p53依赖性细胞凋亡

数据链接：

https://www.omicsdi.org/dataset/biomodels/BIOMD0000001007 数据链接链接失效反馈

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资源简介：

Its a mechanistic model explaining the impact of p53 om apoptosis decision. This model represents schema 1 of manuscript.

创建时间：

2024-09-02

Dataset for: Interaction of replication protein A with two acidic peptides from human Bloom syndrome protein

蛋白质相互作用

DNA损伤响应

Bloom syndrome protein (BLM) is one of five human RecQ helicases which maintain genomic stability. Interaction of BLM with replication protein A (RPA) stimulates the DNA unwinding ability of BLM. The

NIAID Data Ecosystem70

RNA-seq profiling of 22Rv1 prostate cancer cells exposed to repeated DNA damage for 6 weeks.. RNA-seq profiling of 22Rv1 prostate cancer cells exposed to repeated DNA damage for 6 weeks.

前列腺基因表达

DNA损伤响应

RNA-seq profiling of 22Rv1 prostate cancer cell line either untreated, 6 weeks in culture (age matched) or treated daily for 6 weeks with 1 microgram per ml phleomycin to induce DNA damage (n=3 per sa

NIAID Data Ecosystem30

Loss of Atrx Sensitizes Cells to DNA Damaging Agents through p53-Mediated Death Pathways

DNA损伤药物敏感性

p53依赖性细胞凋亡

Prevalent cell death in forebrain- and Sertoli cell-specific Atrx knockout mice suggest that Atrx is important for cell survival. However, conditional ablation in other tissues is not associated with

NIAID Data Ecosystem30

Translational and transcriptional responses of fission yeast to MMS

DNA损伤响应

裂殖酵母基因表达

Translational and transcriptional responses of fission yeast to MMS

ChEBI2020-11-18 更新40

An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis

植物基因功能

DNA损伤响应

ATM is a gene mutated in the human disease ataxia telangiectasia with reported homologues in yeast, Drosophila, Xenopus and mouse. Whenever mutants are available they all indicate a role of this gene

PubMed Central2000-04-15 更新30

Zhang2007 - Mechanism of DNA damage response (Model1)

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