The 29-kDa FK506 binding protein (FKBP) gene is the only peptidyl-prolyl cis-trans isomerase (PPIase) gene in the genome of Pyrococcus horikoshii. We characterized the function of this FKBP (PhFKBP29)
AlphaFold is the state of the art method for prediction of 3D structures of proteins from the amino acid sequence by neural networks. One of the outputs of AlphaFold is a probability profile of inter-
PDB: 3G04, Crystal structure of TSH receptor in complex with human mAb autoantibody M22 (311K, 38°C, 400 ns): random seed #4 > RMSD, SASA, RMSF, Rg, H-bonds
Regression correlation coefficients (R2) and characteristic unfolding parameters k and Δm for the unfolding of bovine heart cytochrome c induced by guanidine hydrochloride and urea.