Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid Tumor

NIAID Data Ecosystem2026-03-13 收录

儿科肿瘤治疗

表观遗传药物靶点

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE196058 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2022-02-07

Crystal structure of the first bromodomain of human BRD4 in complex with DINACICLIB

蛋白质-药物复合物结构

表观遗传药物靶点

Crystal structure of the first bromodomain of human BRD4 in complex with DINACICLIB Descriptor: 1,2-ETHANEDIOL, 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amin

Protein Data Bank Japan2023-09-20 更新40

Crystal structure of JmjC domain of human histone demethylase UTY with S21056a

组蛋白去甲基化

表观遗传药物靶点

Crystal structure of JmjC domain of human histone demethylase UTY with S21056a Descriptor: 1,2-ETHANEDIOL, 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propan-1-ol,

Protein Data Bank Japan2024-01-10 更新20

Table 2 - Assessing the cost and economic impact of tertiary-level pediatric cancer care in Tanzania

疫苗卫生经济学评估

儿科肿瘤治疗

Table 2 - Assessing the cost and economic impact of tertiary-level pediatric cancer care in Tanzania

Figshare2022-11-18 更新10

DataSheet_6_Combination Treatment of CI-994 With Etoposide Potentiates Anticancer Effects Through a Topoisomerase II-Dependent Mechanism in Atypical Teratoid/Rhabdoid Tumor (AT/RT).docx

儿科肿瘤治疗

去乙酰酶研究

PurposeAtypical teratoid/rhabdoid tumor (AT/RT) is arising typically in young children and is associated with a dismal prognosis which there is currently no curative chemotherapeutic regimen. Based on

NIAID Data Ecosystem30

MOESM9 of BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity

表观遗传药物靶点

癌症转录调控

Additional file 9: Table S6. List of all clusters and TSSs belonging to each of them (represented by their gene and transcript name) in MV4;11 and K562 as defined in Fig.Â 3c.

Figshare2019-07-02 更新10

Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid Tumor

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