Modulation of Neurodegeneration by CSFR1 Inhibition in an a-synuclein model of DLB/PD

we treated a widely used and extensively studied synucleinopathy model of transgenic mice (Line 61) with PLX3397 and analyzed their neuropathology, behavioral deficits, and microglial transcriptomes. Overall design: Gene expression profiling analysis of RNA-seq data following CSFR1 inhibition in mouse brain microglia.