Room-temperature X-ray structure of SARS-CoV-2 main protease in complex with GC-376
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Room-temperature X-ray structure of SARS-CoV-2 main protease in complex with GC-376 Descriptor: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase Authors: Kovalevsky, A, Kneller, D.W, Coates, L. Deposit date: 2022-04-01 Release date: 2022-10-05 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS-CoV-2 main protease catalytic domain. Commun Biol, 5, 2022
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2022-04-01
