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Effect of hiPSI <i>TTN</i> truncating variants, a 0.1 change in fraction of genetic similarity to the AFR reference population, and the interaction of the two covariates in logistic regression analysis of Afib risk accounting for age, sex, and the first five genetic PCs. hiPSI = high percentage spliced in; Afib = Atrial fibrillation; UCB = upper confidence bound; LCB = lower confidence bound; AFR = genetically similar to the 1000 Genomes Project African reference population.

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Effect of hiPSI TTN truncating variants, a 0.1 change in fraction of genetic similarity to the AFR reference population, and the interaction of the two covariates in logistic regression analysis of Afib risk accounting for age, sex, and the first five genetic PCs. hiPSI = high percentage spliced in; Afib = Atrial fibrillation; UCB = upper confidence bound; LCB = lower confidence bound; AFR = genetically similar to the 1000 Genomes Project African reference population.

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2025-06-13
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