BTK1 COCRYSTALLIZED WITH RN983
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BTK1 COCRYSTALLIZED WITH RN983 Descriptor: 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-5-[[5-(1-methylpiperidin-4-yl)pyridin-2-yl]amino]-6-oxidanylidene-pyridazin-3-yl]pyridin-2-yl]phthalazin-1-one, Tyrosine-protein kinase BTK Authors: Gardberg, A.S. Deposit date: 2016-09-20 Release date: 2017-05-24 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling. Mol. Pharmacol., 91, 2017
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2016-09-20
