Multiome analysis of stromal cells derived from hematological malignancies

NIAID Data Ecosystem2026-05-10 收录

肿瘤微环境

血液肿瘤基质细胞信号调控

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https://www.ncbi.nlm.nih.gov/sra/DRP016874 数据链接链接失效反馈

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This project aims to explore the regulators of signal pathways that are suppressed by tumor cells in MSCs derived from hematological malignancies.

创建时间：

2026-01-02

Gene expression profile of AT1-like cells in monoculture or cocultured with control or shEphB6-depleted D2.0R-EGFP cells

肿瘤微环境

微生物共培养转录组

We studied how crosstalk with disseminated dormant breast cancer cells affects transcriptome of AT1-like cells and the requirement of EphB6 expression in the cancer cells for this genetic program Over

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Table_1_Risk Signature of Cancer-Associated Fibroblast–Secreted Cytokines Associates With Clinical Outcomes of Breast Cancer.xlsx

癌症预后预测

肿瘤微环境

Cancer-associated fibroblasts (CAFs) are key components in tumor microenvironment (TME). The secreted products of CAFs play important roles in regulating tumor cells and further impacting clinical pro

NIAID Data Ecosystem30

A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer. Zheng et al.

肿瘤微环境

Warburg效应

Pancreatic ductal adenocarcinoma (PDAC) features substantial matrix stiffening and reprogrammed glucose metabolism, particularly the Warburg effect. However, the complex interplay between these traits

NIAID Data Ecosystem00

Table_1_Comprehensive Genomic Characterization of Tumor Microenvironment and Relevant Signature in Clear Cell Renal Cell Carcinoma.xlsx

肿瘤微环境

基因组学

PurposeTo systematically investigate the characterization of tumor microenvironment (TME) in clear cell renal cell carcinoma (ccRCC), we performed a comprehensive analysis incorporating genomic altera

NIAID Data Ecosystem30

Spatial transcriptomics of primary cutaneous melanoma

皮肤黑色素瘤空间转录组

肿瘤微环境

We performed spatial transcriptomics on primary cutaneous melanoma samples to characterise the tumour microenvironment Overall design: Two primary cutaneous melanoma FFPE samples were analysed using s

NIAID Data Ecosystem10

Multiome analysis of stromal cells derived from hematological malignancies

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