Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae [Sequence Data]

The replication of eukaryotic chromosomes is organized temporally and spatially within the nucleus through epigenetic regulation of replication origin function真核染色体的复制在细胞核内通过对复制起始位点（replication origin）功能的表观遗传调控（epigenetic regulation），实现了时间与空间层面的有序组织。