Gene expression profile of liver obtained from liver-specific LPIAT1 KO (LKO) mice on chow or high fat diet (HFD).

To investigate gene expression changes induced by LPIAT1 depletion, Lpiat1F/F and LKO mice were fed high fat diet (HFD) or chow for 18 weeks from 6 weels old and microarray gene profiling were performed. Categorization of the differentially expressed genes between HFD-fed Lpiat1f/f and LKO mice, in relation to their functions in biological pathways, revealed an enrichment of genes involved in inflammation and fibrosis 4 samples