PDGF-B blocking antibody bound to PDGF-BB

PDGF-B blocking antibody bound to PDGF-BB Descriptor: Platelet-derived growth factor subunit B, anti-PDGF-BB antibody - Light Chain, anti-PDGF-BB antibody - Heavy chain Authors: Kuai, J, Mosyak, L, Tam, M, LaVallie, E, Pullen, N, Carven, G. Deposit date: 2014-05-12 Release date: 2015-03-11 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta. Biochemistry, 54, 2015