Transcriptome of S. aureus in the presence or absence of biofilm inhibitor

A small compound named JBD1, identified by HTS of small molecules, inhibits S. aureus biofilm formation. As JBD1 induced multiple phenotypic changes, it was hypothesized that it would also affect the gene expression profile of S. aureus. To investigate this, total RNA extracted from S. aureus cells cultured in the presence/absence of JBD was sequenced.