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Additional file 2: Figure S1. of HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers

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Quality control studies of the shRNA screens. a Representative image showing the Pearson and Spearman correlation among the triplicates for T = 10 in the SUM149 cell line. b GO-term and KEGG-pathway analyses using genes commonly depleted in several cell lines (p <0.05 in >=3 cell lines, 2,555 genes) show enrichment of genes related to essential functions. c Essential genes depleted in our shRNA screen cell lines overlapped significantly with compiled screens across 72 cell lines and subtypes of cancer (Fisherâ s exact test). (EPS 3172 kb)

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2016-12-16
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