Stem cell quiescence acts as a tumor suppressor mechanism in hair follicle initiated squamous tumors

ChEBI2013-10-28 更新2026-07-21 收录

鳞状肿瘤机制

干细胞研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-51765 数据链接链接失效反馈

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资源简介：

Stem cell quiescence acts as a tumor suppressor mechanism in hair follicle initiated squamous tumors

创建时间：

2013-10-28

人多能干细胞来源的神经中胚层间充质干细胞的特性及治疗应用

干细胞研究

治疗应用

理由：间充质干细胞（MSC）由于其多效性，在治疗包括自身免疫性疾病、炎症性疾病等在内的各种疾病方面具有巨大的前景。然而，从不同的基于MSC的临床试验中获得了大量不一致的数据，这可能部分归因于MSC之间的功能异质性。在此，我们试图从人类多能干细胞（hPSC）中获得具有神经内胚层来源的同质间充质干细胞，并评估其功能特性。方法：使用生长因子和/或小分子将人多能干细胞（hPSC）分化为神经内胚层祖细胞（N

干细胞与再生医学数据中心2023-02-02 更新220

ena-DATASET-KNIH-14-12-2017-02:30:27:553-100 - samples

表观遗传学

干细胞研究

A ADMSC01_ChIP-Seq(H3K27me3) paired end data for adipose-derived mesenchymal stroaml cellsEGA dataset EGAD00001003854

NIAID Data Ecosystem110

Enhanced Pluripotent Cell Function through miR-203-mediated Control of DNA Methylation

干细胞研究

DNA甲基化

Maintaining a full differentiation potential along self-renewal ability is a major property of stem cells during development and regeneration. miR-203 is a microRNA previously involved in skin differe

干细胞与再生医学数据中心2022-02-20 更新80

Hematopoietic stem/progenitor cells HELP-tagging cytosine methylation data

干细胞研究

基因组变异

Using HELP-Tagging, we defined the cytosine methylation profiles of hematopoietic stem/progenitor cells (CD34+) from umbilical cord blood in 29 healthy newborns. We found substantial variation of DNA

NIAID Data Ecosystem120

PRC1 and PRC2 Are Not Required for Targeting of H2A.Z to Developmental Genes in Embryonic Stem Cells

表观遗传调控

干细胞研究

The essential histone variant H2A.Z localises to both active and silent chromatin sites. In embryonic stem cells (ESCs), H2A.Z is also reported to co-localise with polycomb repressive complex 2 (PRC2)

NIAID Data Ecosystem90

Stem cell quiescence acts as a tumor suppressor mechanism in hair follicle initiated squamous tumors

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