Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae [Array Data]

The replication of eukaryotic chromosomes is organized temporally and spatially within the nucleus through epigenetic regulation of replication origin function真核染色体的复制过程在细胞核内，通过对复制起点（replication origin）功能的表观遗传调控，实现了时间与空间上的有序组织。