Me-RIP- Sequencing Analysis of normal and senescent nucleus pulposus cells Transcriptomes. Me-RIP- Sequencing Analysis of normal and senescent nucleus pulposus cells Transcriptomes

N6-methyladenosine (m6A) is the most prevalent modification of eukaryotic cells st post-transcriptional level. The goals of this study are to compare the N6-methyladenosine modification of transcripts in normal and senescent nucleus pulposus cells using Me-RIP-seq Overall design: nucleus pulposus cells N6-methyladenosine profiles of three groups of normal human nucleus pulposus cells and three groups of senescent human nucleus pulposus cells isolated and cultured from human nucleus pulpopsus tissues.