NACHT domain of NLRP3 in complex with DFV890
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NACHT domain of NLRP3 in complex with DFV890 Descriptor: 1-[azanyl-oxidanylidene-[2-(2-oxidanylpropan-2-yl)-1,3-thiazol-5-yl]-$l^{6}-sulfanylidene]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... Authors: Dekker, C. Deposit date: 2024-11-18 Release date: 2025-03-19 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2.771 Å) Cite: Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor. J.Med.Chem., 68, 2025
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2024-11-18



