官方服务:
资源简介:
22Rv1_ATAC_1nM-DHT_rep2
应用场景:
创建时间:
2023-03-08
相关数据集
ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [ATAC]
We report the effects of ERG on prostate tumorigenesis, ERG-mediated oncogene addiction, and downstream AR signaling pathways. We determined that ERG facilitates AR-signaling and mediates transformati
NIAID Data Ecosystem70
Loss of Feedback Regulation between FAM3B and Androgen Receptor Driving Prostate Cancer Progression. Loss of Feedback Regulation between FAM3B and Androgen Receptor Driving Prostate Cancer Progression
TMPRSS2-ERG gene fusion is one of the most frequent genetic alterations in prostate cancer (PC). Through a systematical survey of the loss of interstitial genes and patient outcomes, we nominated FAM3
NIAID Data Ecosystem60
Androgen Receptor Signaling Regulates the Transcriptome of Prostate Cancer Cells by Modulating Global Alternative Splicing. Androgen Receptor Signaling Regulates the Transcriptome of Prostate Cancer Cells by Modulating Global Alternative Splicing
HTA2.0 affy array was used to study the effect of androgen inhibitors on alternative splicing in LNCaP cells Overall design: To study the effect of pharmacological manipulation of AR signaling in pros
NIAID Data Ecosystem40
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance. GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance
Genomic amplification of the androgen receptor (AR) is an established mechanism of antiandrogen resistance in prostate cancer. Here we show that the magnitude of AR signaling output, independent of AR
NIAID Data Ecosystem70
Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing. Mus musculus
We used RNA-seq to compare the gene expression profiles of adult mouse prostate luminal cells and luminal cells that have the androgen receptor (AR) gene deleted. Our analyses show that AR-null lumina
NIAID Data Ecosystem40



