In vitro antimycobacterial MICs and cytotoxicities of wollamide B analogues.

Figshare2017-04-19 更新2026-04-29 收录

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In vitro antimycobacterial MICs and cytotoxicities of wollamide B analogues.

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2017-04-19

Complete analysis of data from screening for antitubercular activity and physico chemical properties of the hit compounds.

抗结核药物

化合物活性分析

Rifampicin and Isoniazid were taken as controls. MIC values for controls against M. smegmatis are Rif-2.43±0.02μM and Inh-11.03±0.05 μM and H37Rv are Rif-0.08±0.01μM and Inh-0.22±0.3 μM.

NIAID Data Ecosystem60

Silica catalyzed one pot synthesis of hybrid thiazolidin-4-one derivatives as anti-tubercular and anti-inflammatory agent by attenuating COX-2 pathway

药物化学

抗结核药物

A novel series of a hybrid class of hybrid thiazolidin-4-one derivatives were designed and synthesized through one-pot catalytic synthesis. The reaction was catalyzed in the presence of silica-H 2

DataCite Commons2020-08-26 更新40

Xestospongia muta derived marine actinomycetes. actinomycetes

海洋微生物药物发现

抗结核药物

Strains of various actinomycetes genera were isolated from a Caribbean giant barrel sponge (X.muta) and investigated for the production of compounds that inhibit Mycobacterium

NIAID Data Ecosystem30

A competitive activity-based protein profiling platform yields cell wall synthesis inhibitors active against replicating and non-replicating Mycobacterium tuberculosis

抗结核药物

细胞壁生物学

The identification and validation of a small molecule's targets is a major bottleneck in the discovery process for tuberculosis antibiotics. Activity-based protein profiling (ABPP) is an efficient too

NIAID Data Ecosystem40

In vitro evaluation of nine imidazo[2,1-b]thiazole-5-carboxamides, Q203 and BTZ043 against replicating and non-replicating Mtb, cellular toxicity and aqueous solubility determination.

抗结核药物

体内药效评估

In vitro evaluation of nine imidazo[2,1-b]thiazole-5-carboxamides, Q203 and BTZ043 against replicating and non-replicating Mtb, cellular toxicity and aqueous solubility determination.

Figshare2020-01-06 更新30

In vitro antimycobacterial MICs and cytotoxicities of wollamide B analogues.

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