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Synthesis of 2,4-Diiodoquinolines via the Photochemical Cyclization of <i>o</i>-Alkynylaryl Isocyanides with Iodine

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NIAID Data Ecosystem2026-03-06 收录
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Upon photoirradiation of o-alkynylaryl isocyanides in the presence of iodine, the intramolecular cyclization of o-alkynylaryl isocyanides proceeds to afford the corresponding 2,4-diiodoquinolines in good yields. 2,4-Diiodoquinolines can be employed in transition metal-catalyzed cross-coupling reactions.

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2016-02-23
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