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The re-ranked repurposed drugs for the respective fibrotic diseases.

NIAID Data Ecosystem2026-03-12 收录

数据链接：

https://figshare.com/articles/dataset/The_re-ranked_repurposed_drugs_for_the_respective_fibrotic_diseases_/14383278 数据链接链接失效反馈

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The re-ranked repurposed drugs for the respective fibrotic diseases.

应用场景：

创建时间：

2021-04-07

纤维化治疗

CFTR药物研究

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding for a chloride ion channel. Membrane expression of CFTR is negatively regul

NIAID Data Ecosystem70

nNO measurements before and after two months and one year of ivacaftor therapy.

纤维化治疗

呼吸道疾病监测

nNO measurements before and after two months and one year of ivacaftor therapy.

NIAID Data Ecosystem50

Administration of glutaredoxin-1 attenuates liver fibrosis caused by aging and non-alcoholic steatohepatitis. Administration of glutaredoxin-1 attenuates liver fibrosis caused by aging and non-alcoholic steatohepatitis

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非酒精性脂肪性肝炎

Glutaredoxin-1 (Glrx) controls redox signaling and has an anti-apoptotic function. We evaluated the role of Glrx on hepatic cell damage and fibrosis induced by a high-fat diet. We fed mice a high-fat

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Chemotext: A Publicly Available Web Server for Mining Drug–Target–Disease Relationships in PubMed

药物-靶点-疾病关系挖掘

药物重定位

Elucidation of the mechanistic relationships between drugs, their targets, and diseases is at the core of modern drug discovery research. Thousands of studies relevant to the drug–target–disease (DTD)

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YFP_quenching_assay_data

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离子通道功能检测

Data for manuscript: Gain-of-function CFTR restores essential epithelial function with greater efficacy than wildtype or codon optimized CFTR when expressed in cystic fibrosis airway cells.

Figshare2023-08-09 更新40

The re-ranked repurposed drugs for the respective fibrotic diseases.

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