Effect of terminal ischemia/anoxia on the ECS diffusion parameters, ADC_W and extracellular K⁺ concentration in α-syn +/+ and α-syn −/− mice <i>in vivo</i>.

The values are presented as mean ± S.E.M. Asterisks (*-p<0.05; **-p<0.01; ***-p<0.001) indicate significant differences between the values in α-syn +/+ and α-syn −/− animals; crosshatches (#-p<0.05; ##-p<0.01; ###-p<0.001) indicate significant differences between control values and those obtained under experimental conditions in the same group of animals and crosses (†-p<0.05; ††-p<0.01; †††-p<0.001) indicate significant difference between values in vitro and in vivo. The mean values of the maximum change during terminal ischemia/anoxia correspond to the 30th minute after cardiac arrest. Abbreviations: extracellular space volume fraction (α), tortuosity (λ), non-specific uptake (k′), extracellular potassium concentration ([K+]e), apparent diffusion coefficient (ADCW) number of animals (N).