Physiologically-based Pharmacokinetic (PBPK) model of estradiol disposition in humans. Based on Sier et al_2017_estrogen PBPK_simple (MODEL1711210001), but with intrinsic (i.e. liver-mediated) clearan
Drug precipitation in the nephrons of the kidney can cause drug-induced crystal nephropathy (DICN). To aid mitigation of this risk in early drug discovery, we developed a physiologically based in sili
Accompanying OMEX file for the Physiome article "Reproducibility Study on a PBPK Model of FcRn-Mediated Recycling for Large Molecules".An OMEX archive is the Open Modelling Exchange format, the techni
