GLP-1 induced transcriptomic profile in INS-1 cells

Alliance of Genome Resources2026-08-01 收录

GLP-1受体激动剂机制

胰腺β细胞转录组

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https://www.ncbi.nlm.nih.gov/gds/?term=GSE102003 数据链接链接失效反馈

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Conclusion: GLP-1 has a varied effect on the transcriptomic profile of INS-1 cells.

结论：胰高血糖素样肽-1（GLP-1）对INS-1细胞的转录组谱具有多样的效应。

Gene expression of Cell populations sorted from exocrine cells reprogrammed to beta-like cells

细胞重编程

胰腺β细胞转录组

Bulk MARS-seq analysis of gene expression in reprogrammed exocrine cells exhibit many similarities to native beta cells. Reprogrammed cells are enriched for expression of genes that are direct targets

NIAID Data Ecosystem50

Expression data from pancreatic beta cells isolated from differentially weaned mice.

胰腺β细胞转录组

断奶影响基因表达

Transcriptome analysis reveals that in pancreatic beta cells weaning increases the expression of genes involved in replication licensing, suggesting a mechanism to increased responsiveness to the mito

NIAID Data Ecosystem40

Shorgun metagenomics of T2DM human gut microbes treated with GLP-1 drug

糖尿病肠道微生物组

GLP-1受体激动剂机制

GLP-1 improves endothelial cell function indicators in middle-aged and elderly diabetic patients, which may be related to its alteration of the population numbers of gut microbiota.We conduct this pro

NIAID Data Ecosystem30

Gene expression changes in response to doxycyline-induced expression of proinsulin (C96Y)-GFP in an INS-1 insulinoma cell line. Rattus norvegicus

内质网应激

胰腺β细胞转录组

A doxycyline-inducible INS-1 insulinoma cell line expressing proinsulin (C96Y)-GFP was engineered. Addition of doxycyline causes the production of the proinsulin (C96Y)-GFP, which is retained in the e

NIAID Data Ecosystem50

STX4 Over-Expression in Human islets. STX4 Over-Expression in Human islets

胰腺β细胞转录组

STX4过表达与趋化因子调控

We have used RNA-seq to identify transcripts expressed in human islets harboring beta cells transduced to overexpress STX4 and induce chemokine ligand by adenoviral transduction Overall design: 3 huma

NIAID Data Ecosystem40

GLP-1 induced transcriptomic profile in INS-1 cells

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