A chemical investigation of Streptomyces sp. SCSIO 40069 resulted in the isolation of a series of aromatic polyketides with rare skeletons, including five new compounds RM18c–RM18g (1–5) and three kno

NIAID Data Ecosystem50

Novel bacterial methionine aminopeptidase inhibitors

抗菌药物发现

细菌酶抑制

Novel bacterial methionine aminopeptidase inhibitors

NIAID Data Ecosystem40

Elucidation of critical chemical moieties of metallo-β-lactamase inhibitors and prioritisation of target metallo-β-lactamases

抗菌药物发现

金属β-内酰胺酶抑制剂

The urgent demand for effective countermeasures against metallo-β-lactamases (MBLs) necessitates development of novel metallo-β-lactamase inhibitors (MBLIs). This study is dedicated to identifying cri

DataCite Commons2024-12-26 更新100

Aminoglycoside–Peptide Nucleic Acid (PNA) conjugates against Gram-negative bacteria

抗菌药物发现

基因沉默疗法

Research data in the form of Tab-delimited text files: growth (OD600) of the bacterial strains (E. coli AS19, E. coli K12, E. coli WR 3551/98, E. coli K12 mutant lacking sbmA gene, E. coli ML-35 and S

DataCite Commons2026-03-04 更新50

Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

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