Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy

ChEBI2013-05-01 更新2026-07-21 收录

肝病分子机制

大脑皮层基因表达谱

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-41919 数据链接链接失效反馈

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Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy

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2013-05-01

RNA-seq analysis of brain tissue treated by VEGFC in BDL-induced cirrhotic rat with hepatic encephalopathy

肝病分子机制

脑膜淋巴管生成

Conclusion: Promoting meningeal lymphatic drainage and enhancing waste clearance improves HE. Manipulation of meningeal lymphangiogenesis could be a new therapeutic strategy for the treatment of HE.

Alliance of Genome Resources110

Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy

肝病分子机制

脑部基因表达谱

Hepatic encephalopathy (HE) is a frequent complication of liver cirrhosis and is seen as the clinical manifestation of a low grade cerebral edema associated with oxidative-nitrosative stress, however,

NIAID Data Ecosystem50

Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients. Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients

肝病分子机制

疾病多组学分析

Patients with liver cirrhosis may develop minimal hepatic encephalopathy (MHE) which affects their quality of life and life span. It has been proposed that a shift in peripheral inflammation triggers

NIAID Data Ecosystem30

IFN-b treatment of primary murine hepatocytes. IFN-b treatment of primary murine hepatocytes

干扰素免疫调节

肝病分子机制

Primary murine hepatocytes were isolated from C57Bl/6J (wild type) animals and treated with 1000 U/mL IFN-b for 24h and compared to time-matched untreated controls. Overall design: We sequenced in vit

NIAID Data Ecosystem70

Table6_Cell Differentiation Trajectory in Liver Cirrhosis Predicts Hepatocellular Carcinoma Prognosis and Reveals Potential Biomarkers for Progression of Liver Cirrhosis to Hepatocellular Carcinoma.XLSX

肝细胞癌预后

肝病分子机制

Most hepatocellular carcinoma (HCC) patients occur on a background of liver cirrhosis, the molecular mechanisms of liver cirrhosis and its progression to HCC remain to be fully elucidated. Single cell

NIAID Data Ecosystem40

Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy

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