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Convenient Synthetic Route to an Enantiomerically Pure FMOC α-Amino Acid

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NIAID Data Ecosystem2026-03-06 收录
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A strategy for the facile α-amination of carboxylic acid menthyl esters is described. The resulting diastereomers, readily separable, can be individually carried on to each enantiomer of the FMOC α-amino acid. A variety of unnatural side chains were compatible with this approach. The menthyl ester was easily removed from the FMOC α-amino acid without racemization.

创建时间:
2008-12-05
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