Supporting figures.

Figure A in S1 File. Dextran sodium sulfate (DSS) induces caspase-1-mediated IL-1β release from murine macrophages. Figure B in S1 File. Apoptotic cell treatment in nlrp3 deficient mice. Figure C in S1 File. Negligible IL-1β secretion in nlrp3 deficient mice. Figure D in S1 File. Influence of apoptotic cells and LPS on IL-1β and caspase-1 activation. Figure E in S1 File. Apoptotic cell treatment inhibits cyclooxygenase-2 (COX-2) in DSS-induced colitis. Figure F in S1 File. Apoptotic cell treatment inhibits Iκ-Bα phosphorylation in DSS-induced colitis. (DOCX)