Cancer vaccines, reassembled from whole tumor tissue components, were applied to demonstrate the across-cancer immune responses, thanks to inducing pan-clones T cells immune responses. It is demonstra

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DYNAMIC INTERPLAY BETWEEN TUMOR AND MICRO-ENVIRONMENT DURING MULTIPLE MYELOMA DISEASE PROGRESSION

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Characterizing the changes between normal, pre-malignant and active disease states increases our understanding of multiple myeloma (MM) pathogenesis and helps further the identification of novel preve

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Cancer cell-intrinsic XBP1 mediates immunosuppressive reprogramming of intratumoral myeloid cells by promoting cholesterol production. Cancer cell-intrinsic XBP1 mediates immunosuppressive reprogramming of intratumoral myeloid cells by promoting cholesterol production

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A hostile microenvironment in tumor tissues disrupts endoplasmic reticulum homeostasis and induces the unfolded protein response (UPR). A chronic UPR in both cancer cells and tumor-infiltrating leukoc

NIAID Data Ecosystem20

Immunophenotypes of administered DAKs and RNF43 peptide-pulsed DC.

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