Catalytic Divergent Synthesis of 3<i>H</i> or 1<i>H</i> Pyrroles by [3 + 2] Cyclization of Allenoates with Activated Isocyanides
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The cyclization of allenoates with activated isocyanides was reported for the first time. While Ag catalysis led to an unprecedented enantioselective synthesis of 3H pyrroles, a simple procedure using PPh3 produced a wide range of polysubstituted 1H pyrroles with high efficiency.
创建时间:
2016-02-15



