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CUT&RUN experiment in colon cancer cells (HCT116, DLD1 and SW620), assessing TBX3 genomic occupancy

ChEBI2024-01-01 更新2026-07-12 收录

转录因子结合位点检测

结肠癌表观遗传

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-13646 数据链接链接失效反馈

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资源简介：

CUT&RUN experiment in colon cancer cells (HCT116, DLD1 and SW620), assessing TBX3 genomic occupancy

应用场景：

创建时间：

2024-01-01

转录因子结合位点检测

ChIP-exo技术

Chromatin immunoprecipitation (ChIP-chip and ChIP-seq) assays identify where proteins bind throughout a genome. However, DNA contamination and DNA fragmentation heterogeneity produce false positives (

NIAID Data Ecosystem40

Additional file 6 of DNA methylation analysis of normal colon organoids from familial adenomatous polyposis patients reveals novel insight into colon cancer development

结肠癌表观遗传

类器官分子分析

Additional file 6: Table S4. Summary of qPCR and RNA-seq analysis performed on selected gene targets. Positive fold changes and t values indicate increased expression in TCGA-COAD tumor and FAP colon

Figshare2024-02-12 更新20

TF ChIP-seq from K562 (ENCSR645ZWR)

转录因子结合位点检测

基因组学分析

ChIP-Seq on K562 For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14

NIAID Data Ecosystem10

DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways [BrafV637E knock-in ]

结肠癌表观遗传

CpG岛甲基化

Promoter hypermethylation divides colon cancers into subtypes with and without a CpG island methylator phenotype (CIMP). Here, we performed genome-wide DNA methylation profiling of colonic normal and

NIAID Data Ecosystem30

Transcriptomic and epigenomic profiling of H3K27me3 demethylases inhibitor GSK-J4 induced changes in colon cancer cells (RNA-Seq)

结肠癌表观遗传

药物诱导转录组分析

H3K27me3 demethylases UTX and JMJD3 play vital roles in development and disease, including cancer. Therefore, we systematically investigated the impact of inhibition of these two demethylases using a

NIAID Data Ecosystem20

CUT&RUN experiment in colon cancer cells (HCT116, DLD1 and SW620), assessing TBX3 genomic occupancy

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