Microglia are involved in Alzheimer's disease (AD) by adopting activated phenotypes. How ageing in the absence or presence of Ã-amyloid (AÃ) deposition in different brain areas affects this response
The lineage-determining transcription factor IRF8's function in microglia is unclear. Our study aims to shed light on this by analyzing the genome-wide, temporal transcriptome profiles of wild-type an