Ras/cAMP signal transduction, perturbations

NIAID Data Ecosystem2026-03-07 收录

RAS信号通路

信号转导扰动

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2927 数据链接链接失效反馈

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资源简介：

Disruption of Ras/cAMP signaling by perturbation of pathway elements and controlled cAMP concentration. All cultures grown in SC medium. Keywords: other to be completed by submitter

创建时间：

2012-03-16

Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer

癌症靶向治疗

RAS信号通路

The Ras-family small GTPase RAB25 is involved in numerous aspects of endosomal protein trafficking and cell polarity. Recent evidence has established a role for RAB25, as well as related RAB-family an

NIAID Data Ecosystem80

Solution Structure of the N-terminal Ras-binding Domain (RBD) in Human a-Raf Kinase

蛋白质结构解析

RAS信号通路

Solution Structure of the N-terminal Ras-binding Domain (RBD) in Human a-Raf Kinase Descriptor: A-Raf proto-oncogene serine/threonine-protein kinase Authors: Zhao, C, Tochio, N, Koshiba, S, Inoue, M,

Protein Data Bank Japan2024-05-29 更新40

Supplementary Table 4 from Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities

CRISPRi筛选

RAS信号通路

Results from the single-target sgRNA screen in A549-Cas9 cells. The columns are as follows. Symbol : HUGO gene symbol ; EnsemblID : EnsEMBL identifier ; GeneID : Entrez Gene ID ; GeneInfo : Name of pr

Figshare2020-12-01 更新30

Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2

癌症转录调控

RAS信号通路

Aberrant activation of RAS/MAPK signaling is a driver of over one third of all human carcinomas. The homologous transcription factors ETS1 and ETS2 mediate the activation of gene expression programs d

NIAID Data Ecosystem50

NRASG12V mediates self renewal in AML [RNA-Seq]. Mus musculus

急性髓系白血病自我更新

RAS信号通路

Mutant RAS oncoproteins activate signaling molecules that drive oncogenesis in multiple human tumors including acute myelogenous leukemia (AML). However, the specific function of these pathways in AML

NIAID Data Ecosystem40

Ras/cAMP signal transduction, perturbations

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