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Binding coefficients for candidate aptamers versus IL 6 and HSA.

NIAID Data Ecosystem2026-05-02 收录

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https://figshare.com/articles/dataset/Binding_coefficients_for_candidate_aptamers_versus_IL_6_and_HSA_/28404325 数据链接链接失效反馈

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资源简介：

Binding coefficients for candidate aptamers versus IL 6 and HSA.

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创建时间：

2025-02-12

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癌症靶向治疗

Aptamers are molecules that reveal highly complex and refined molecular recognition properties. These molecules are capable of binding with high affinity and selectivity to targets, ranging from small

NIAID Data Ecosystem90

A sputum bioassay for airway eosinophilia using an eosinophil peroxidase aptamer

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嗜酸性粒细胞分析

We genearted a DNA aptamer against EPX via SELEX protocol using a random DNA library and developed an assay to monitor EPX in patients spitum samples After 15 rounds of selection, the aptamer sequence

NIAID Data Ecosystem50

Bulk affinity Manuscript supporting file

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亲和力测定

The excel file contains modeled distributions of Kd values for progressive rounds of aptamer selection and proposed bulk affinity workflow. The origin file includes the construction of gaussi

NIAID Data Ecosystem40

Systematic Study of in vitro Selection Stringency Reveals How to Enrich High-Affinity Aptamers

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SELEX技术

Library-immobilized SELEX was performed with an N30 stem-loop structured DNA library to isolate an aptamer that binds to the small molecule flunixin. Pools from various trials were sequenced.

NIAID Data Ecosystem80

The primer and library sequences used in this study as well as the sequences of the two aptamers discovered in this work. APTSEB1 was reported in 48 out of 49 sequences.

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核酸序列分析

The primer and library sequences used in this study as well as the sequences of the two aptamers discovered in this work. APTSEB1 was reported in 48 out of 49 sequences.

Figshare2015-12-02 更新40

Binding coefficients for candidate aptamers versus IL 6 and HSA.

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