We report the mutation profile of measles F gene by saturating mutagenesis. We evaluate the mutation rate of measles F gene in pCDNA3 backbone (shuttle plasmid), pEMC backbone (genome plasmid), and RT
The expected number of mutations is the same in each scenario (μ × ℓ is constant). Values are averages over 25 simulations with no sequencing error (ϵ = 0).
Supplementary numerical data. The raw data on the substitution rate constants in the reference L1 sequence (data 1), the resulting Trek database processed with (data 2) and without (data 3) the strand
microarray experiment to test the gene expression in long term lines of mutator and non-mutator yeast. Here we use an experimental evolution approach to investigate the conditions required for evoluti
