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Colon, rectum and rectal tumor organoids. Effects of calcitriol (active form of Vitamin D) treatment

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NIAID Data Ecosystem2026-03-12 收录
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We have established three-dimensional (3D) organoids from healthy colon and rectum tissue and from tumor tissue of patients with rectal cancer. Global transcriptomic analyses reveal differences in gene expression between these stem cell-derived cultures and distinct response to vitamin D. Overall design: 1,25(OH)2D3 and vehicle treated organoids from colon, rectum and rectal tumor tissue are RNA-sequenced

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2020-09-10
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