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Shear Stress and NOTCH1 Regulate Calcification Related Genes in Human Aortic Valve Endothelium

ChEBI2015-05-16 更新2026-07-21 收录

心脏瓣膜钙化机制

生物力学信号调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-47160 数据链接链接失效反馈

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资源简介：

Shear Stress and NOTCH1 Regulate Calcification Related Genes in Human Aortic Valve Endothelium

应用场景：

创建时间：

2015-05-16

心脏瓣膜钙化机制

细胞自噬调控

DiI-labeled M1-polarized macrophages were internalized by aortic valve interstitial cells AVICs, resulting in significantly increased calcium nodule formation and expression of osteogenesis-related ge

NIAID Data Ecosystem60

Atractylenolide 1 targets FLT3 to regulate PI3K to inhibit osteogenic differentiation of human valve interstitial cells

心脏瓣膜钙化机制

天然药物药理

Atractylenolide 1, a natural active ingredient extracted from Atractylodes macrocephala, has been proved to have good anti-inflammatory and anti fibrosis effects. Osteogenic changes induced by inflamm

NIAID Data Ecosystem50

Gene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing.

心脏瓣膜钙化机制

转录组差异分析

Gene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing.

ChEBI2015-12-09 更新30

RNA-sequencing of human aortic valve interstitial cells with or without treatment of cardamonin under the osteogenic induction

心脏瓣膜钙化机制

RNA测序药物靶点

The mRNA sequencing was utilized to analyze differentially expressed genes (DEGs) and related signaling pathways as potential molecular targets involved in cardamonin's anti-calcification activity.

NIAID Data Ecosystem50

心脏瓣膜钙化机制

药物靶点研究

This record contains raw data related to the article"Cyclophilin A Inhibition as Potential Treatment of Human Aortic Valve Calcification". Abstract Calcific aortic valve stenosis (AS) is a patholo

NIAID Data Ecosystem40

Shear Stress and NOTCH1 Regulate Calcification Related Genes in Human Aortic Valve Endothelium

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