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Transcription profiling of testis from wild type mice and mice with a Sertoli-specific ablation of Dicer

Alliance of Genome Resources2026-08-01 收录

支持细胞Dicer敲除转录组

睾丸基因调控

数据链接：

http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=E-TABM-426 数据链接链接失效反馈

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资源简介：

Assess the transcriptomic effects of Sertoli-specific ablation of Dicer in mice

评估小鼠中支持细胞（Sertoli）特异性敲除Dicer所产生的转录组学效应

应用场景：

睾丸基因调控

减数分裂异常

Ikbkap/Elp1 regulates genes involved in spermatogenesis. Ikbkap deficiency causes male infertility by disrupting meiotic progression. In this dataset, we include the expression data for control and Ik

NIAID Data Ecosystem50

Coexpression of Nuclear Receptors and Histone Methylation Modifying Genes in the Testis: Implications for Endocrine Disruptor Modes of Action

内分泌干扰物作用模式

睾丸基因调控

BackgroundEndocrine disruptor chemicals elicit adverse health effects by perturbing nuclear receptor signalling systems. It has been speculated that these compounds may also perturb epigenetic mechani

NIAID Data Ecosystem40

Multigenerational paternal high-fat diet gradually exacerbates environmental stress-induced testicular dysregulated expression of mRNAs in offspring

生殖表观遗传学

睾丸基因调控

To investigate the mechanism by which paternal exposure to high-fat diet (HFD) exacerbates environmental stress-impaired testicular germ cell development in offspring, testicular RNA sequencing was pe

NIAID Data Ecosystem20

Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Agilent expression]

睾丸基因调控

PAX2基因

The epithelium lining the epididymis in the male reproductive tract maintains a luminal environment that promotes sperm cell maturation. This process is dependent on the coordinated expression of many

NIAID Data Ecosystem40

Next Generation Sequencing Facilitates Quantitative Analysis of chromatin interaction of lncRNA Gm4665 with regulatory region of target genes in male germ cells.

lncRNA染色质互作

睾丸基因调控

Purpose: The goals of this study are to examine the possibility that Gm4665 binds to regulatory region of target genes loci in male germ cells. Methods: we performed the Chromatin Isolation by RNA Pur

NIAID Data Ecosystem30

Transcription profiling of testis from wild type mice and mice with a Sertoli-specific ablation of Dicer

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