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Investigating genomic stability of the R26 EYFP locus in MEFs after Cas9-induced DSB

ChEBI2026-05-15 更新2026-07-12 收录

CRISPR-Cas9基因编辑

基因组稳定性

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-16485 数据链接链接失效反馈

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Investigating genomic stability of the R26 EYFP locus in MEFs after Cas9-induced DSB

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创建时间：

2026-05-15

表观遗传调控

基因组稳定性

Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans, and has been implicated in many important biological processes including cell differentiation and reprogramming. Germlin

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Whole-genome sequencing analysis of CRISPR-tolerant mutants. Escherichia coli

CRISPR系统

基因组稳定性

To investigate whether ISs transpositions into cas genes could potentially lead to concurrent transpositions into other genomic loci or induce genomic rearrangements and instability, we performed whol

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Swc4 protects chromatin against genome instability and aneuploidy

染色质生物学

基因组稳定性

In the baker's yeast Saccharomyces cerevisiae, Swc4, Yaf9, Arp4, and Act1 form a submodule shared by histone acetylation NuA4 complex and chromatin remodeling SWR1 complex (SWR1-C). Act1 and Arp4 are

NIAID Data Ecosystem40

BLM prevents instability of structure-forming DNA sequences at common fragile sites

基因组稳定性

DNA修复

Genome instability often arises at common fragile sites (CFSs) leading to cancer-associated chromosomal rearrangements. However, the underlying mechanisms of how CFS protection is achieved is not well

Figshare2018-12-11 更新50

Table_1_Quality Control Strategy for CRISPR-Cas9-Based Gene Editing Complicated by a Pseudogene.docx

CRISPR-Cas9基因编辑

假基因干扰控制

CRISPR-Cas9 mediated gene editing in induced pluripotent stem cells became an efficient tool to investigate biological mechanisms underlying genetic-driven diseases while accounting for the respective

NIAID Data Ecosystem40

Investigating genomic stability of the R26 EYFP locus in MEFs after Cas9-induced DSB

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