Properties of 61 nonstop codons. Shown are corresponding amino acids, relative adaptiveness values for tAI [19, 24], classification of optimal (O) and nonoptimal (N) codons [20], and a binary variable
RNA abundance is controlled by rates of synthesis and degradation. Although mis-regulation of RNA turnover is linked to neurodevelopmental disorders, how it contributes to cortical development is larg
N7-methylguanosine (m7G) modification, routinely occurring at the 5’ cap of mRNA or within tRNA and rRNA, also exists internally in mRNA. Although essential for mRNA translation as well as stress resp