BACKGROUND: Decisions on treatment are guided, not only by the potential for benefit, but also by the nature and severity of adverse drug reactions. However, some researchers have found numerous defic
Additional file 1. Table of domain categories, SSD intervention-related outcome domains, and concept definitions for all 44 outcome domains co-produced with collaborators with lived experience of SSD
Background Phase II clinical trials are a cornerstone of the development in experimental treatments They work as a "filter" for phase III trials confirmation. Surprisingly the attrition ratio in Phase