Tandem Radical Fluoroalkylation–Cyclization: Synthesis of Tetrafluoro Imidazopyridines
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A copper-catalyzed fluoroalkylation–cyclization sequence of alkenes and alkynes enables the synthesis of fluorinated tetra- and dihydroimidazopyridines in moderate to excellent yields within 1 h at 70 °C. This reaction, which is carried out using copper(I) acetate as the catalyst, makes use of a new class of functionalized tetrafluoroethyl reagents based on a hypervalent iodine scaffold.
创建时间：
2016-02-12
